Selective Attention

One morning, while I was riding a bike, I got to thinking about how mood affects attention and how that, in turn, creates a different reality for us depending on what mood we’re in. To think all these thoughts were sparked by my reaction to the image of a dead squirrel… Several weeks ago, it had been an especially dark …

My Brain is Trying to Kill Me

Sometimes brains do terrible things. One of the worst of those things is the suicidal preoccupation that can, eventually, lead to suicide itself. Over the years I have done a lot of thinking about suicide and suicidal preoccupation. One aspect of thoughts of suicide is the data about what happens when someone tries to kill him or herself and is …

Depressed Mothers and Oxytocin

Oxytocin is often brought up in conversations about childbirth. After childbirth, new mothers normally experience surges of oxytocin that increase feelings of maternal bonding, trust, and empathy. In addition to facilitating pair bonding, recent studies have shown oxytocin  plays a greater role in mental health than originally thought. Low levels of oxytocin may be a phenomenon linked to depression. Maternal …

Amygdala Differences in Depressed Individuals

The best way to tackle an illness is to start treatment as early as possible. In the case of depression, recent studies has revealed that there may be a way to identify depression symptoms in children. An fMRI study was conducted on a group of preschool students to see if there were any differences in the brains of depressed and …

The U Pattern of Depression

Over time researchers have observed that depression follows a U pattern. First depression symptoms are high in young adulthood. Like the dip of a U, depression symptoms decrease in midlife, and the rounding back up of the U signifies the return of greater depressive symptoms in later years. The results of some long-term longitudinal studies that investigated the peak in …

A Spoonful of Courage

In a previous post, I shared Linda Graham’s views on resilience from an excerpt from her article Bouncing Back :Rewiring the Brian for Maximum Resilience and Well-Being. After further reading, Graham also discusses the importance of having courage when creating a more positive outlook on life. We have the ability to experience great personal growth when engaging in new things. …

Chronic Depression: What You See Depends on Where You Look

It can be hard to sit with someone with depression, especially chronic depression. For me it is the fact that I am trained to try to enter a person’s world, and understand that world… but the visit to the world of someone who is depressed can be depressing. One of the reasons for this is that they describe lives where …

Stress, Resilience and the Neurobiology of Depression

Dr. Eric Nestler, M.D. believes that when it comes to treating depression, we should be doing better.  Less than half of those with depression get better after receiving maximum treatment. Dr. Nestler describes depression as a broad syndrome hat involves many different diseases. Because the specific causes of depression cannot be identified, this disorder is difficult to treat. In order …

Effects of Vitamin D on Mental Illness

Current Psychiatry posted an article suggesting that vitamin D levels are related to different mental illnesses. Although more than 50% of psychiatric patients are reported to have vitamin D deficiencies, there is still not enough evidence to say that vitamin D supplementation will help with symptoms. One way vitamin D enters our systems is through exposure to sunlight. UV radiation …

Check Your Wallet

Recently, we were writing about the bias that practitioners have that the technique that they they have mastered is the most effective treatment for any condition. We were reminded of this issue very vividly this morning when we met up with one of our favorite people, an older man who has been seeing us for a couple of years. He …

DSM5

In the next few days the American Psychiatric Association is meeting in San Francisco and will announce the latest version of its diagnostic and statistical manual: DSM5. Tom Insel, the Chief of the National Institute for Mental Health, created quite a stir last week by seeming to announce that the new diagnostic manual was an emperor with no clothes. The …

Stress and Your Brain

Stress has a major affect on our bodies and our brain. The release of catecholamines (adrenaline and related chemicals) and cortisol causes significant changes throughout our body that are designed to prepare us for “fight or flight.” By shutting down all non-essential functions the stress response system prepares us for a life and death struggle Nowadays there are no life …

Depression and Heart Disease: Inflammation

A large study published in April of 2013 in the journal Psychoneuroendocrinology followed 667 people with heart disease for 5 years and found that depression appears to lead to inflammation rather than inflammation leading to depression. Excessive inflammation is one of the main causes of heart disease, because it is associated with blockages in the blood vessels that deliver blood to …

Iron for PMS

A recent study suggested that women who consumed higher amounts of iron (from plant not animal sources) had a lower rate of premenstrual symptoms. Those who consumed more than 20 milligrams per day had about a 30% reduction in PMS symptoms compared with those who consumed less than the average amount  (average intake of 9.4 milligrams per day). This study …

Escape from Depression

I met a young woman yesterday who got me thinking about the reasons why I feel so strongly about the work I do as a psychiatrist, helping people with chronic mood problems. She came in for help with what she described as a “mild but chronic depression.” She had already seen one psychiatrist, and he had not been terribly helpful; …

St. John’s Wort

St. John’s Wort is a plant which has been shown in many well controlled clinical trials to be more effective than placebo in treating mild to moderate depression (not transient sadness). In fact the evidence supporting its effectiveness is better than the evidence supporting the effectiveness of some FDA approved anti-depressants.  It does not, in our experience, work as well …

The Gift of Hope

I have never been able to find the short article in the Journal of the American Medical Association that talked about a miraculous treatment for many ailments of the human mind and body… The article was about “hope.” When we have it there is hardly any problem we can’t tackle, and when we lack it every challenge seems insurmountable. This …

Trojan Horse Medications

From time to time we are asked to review the care that people with cycling moods have received, trying to figure out, from a complicated story of medication changes and mood cycles, what to do to get someone out of a period of deep pain and dysfunction. A few years ago I did such a review on a young man …