Phosphatidylserine

Phosphatidylserine may help protect the body against stress and may improve memory and prevent Alzheimer’s dementia. For the last month I have been examining some of the literature on this topic and working with some people in my practice to see if phosphatidylserine seems to be a useful natural supplement. The research literature on phosphatidylserine is intriguing. But first a …

Aerobic Exercise Stimulates Neuron Growth

Moderate aerobic exercise appears to be the best form of exercise to stimulate neuron growth. One of the great challenges facing anyone who has wrestled with depression is how best to counteract the negative effects on brain development and cognitive function that have clearly been linked to recurrent depression. Depression leads directly to reductions in the brain’s growth hormone (brain …

MIND Diet Prevents Memory Loss

Researchers at Rush University have developed a diet (the MIND diet) that appears to be associated with significantly reduced cognitive decline in aging. The diet was developed from three sources of information: the Mediterranean diet (as elsewhere on this blog), the DASH diet for the prevention of hypertension, and a review of the literature on the effects of specific dietary components …

Memory and Cognitive Problems

Memory and/or cognitive problems are the rule rather than the exception in people with mood disorders1. There are a number of reasons for this and figuring out the best approach to these problems is tricky. Mood episodes (episodes of mania, hypomania or depression) appear to be harmful to the brain. Studies find that those with the largest number of episodes …

Brain Cell Formation in Older Brains

Cell formation. Readers of this blog may recall that we reported last year the discouraging findings from Dr. Pasco Rakic (professor of neuroanatomy at Yale University) that there is very little neurogenesis (creation of new neurons) in the brains of older primates (including humans). Now, an article by Kristy Spalding published a few months ago in Cell suggests that the …

Brain Derived Neurotrophic Factor (BDNF) May Prevent Alzheimer’s

Higher blood levels of brain-derived neurotrophic factor (BDNF) appear to protect against Alzheimer’s disease (AD) and other types of dementia, that is the result of a study is published in JAMA Neurology this past month by Sudha Seshadri, M.D., a professor of neurology at Boston University and his colleagues. BDNF is “growth hormone” for the brain. It enhances the creation of connections between …

My Brain Isn’t Working

 Difficulties with cognition and focus are almost universal in folks with moods. In the scientific literature there have been attempts to distinguish between mood related problems and problems that tend to persist regardless of mood state. There is probably nothing that can more profoundly affect our brain’s ability to focus than an episode of depression or mania. These functional brain …

Mood and Cognitive Functioning

Mood can have a profound impact on cognitive functioning. In fact, over the years, we have found that the most likely diagnosis when someone comes in complaining of “suddenly becoming demented” is a mood disorder (people with dementias tends to have a more gradual onset of symptoms and often don’t notice the impairments). There seem to be three types of …