Cognitive Issues and Bipolar Disorder

Does bipolar disorder cause problems with memory, attention focus, speed of thinking and cognition?  Does depression cause dementia, or does it just feel like it?  Are memory problems and cognition issues caused by the medications that control mood episodes?  Is there anything one can do about troubles in thinking and memory related to mood issues? “Suddenly becoming demented” is a …

Cognitive Recovery from Mania

Cognitive recovery from mania or depression seems to lack behind the improvement in mood symptoms. In our experience full cognitive recovery may take up to three months after the mood symptoms have remitted. One way of thinking about this is that an episode of mania, or depression, upsets the normal function of the brain and it takes a while for …

Phosphatidylserine

Phosphatidylserine may help protect the body against stress and may improve memory and prevent Alzheimer’s dementia. For the last month I have been examining some of the literature on this topic and working with some people in my practice to see if phosphatidylserine seems to be a useful natural supplement. The research literature on phosphatidylserine is intriguing. But first a …

Aerobic Exercise Stimulates Neuron Growth

Moderate aerobic exercise appears to be the best form of exercise to stimulate neuron growth. One of the great challenges facing anyone who has wrestled with depression is how best to counteract the negative effects on brain development and cognitive function that have clearly been linked to recurrent depression. Depression leads directly to reductions in the brain’s growth hormone (brain …

Adult ADHD

Adult ADHD May Be Distinct From Childhood ADHD Attention-deficit/hyperactivity disorder (ADHD) in children may be distinct from and unrelated to ADHD in adults, according to a study in the American Journal of Psychiatry. It is long been understood that adult ADHD is the natural extension of childhood onset ADHD. In other words that adults with ADHD began as children with …

Mood Charting for Complicated Problems

Lucy is a single woman who is a professor of anthropology at a local university. She is in her late 30s and she was referred to me for a consultation because of a complicated set of potentially interrelated problems with cognitive impairment, sleep disruption, anxiety, depression, a seizure disorder, and migraine headaches. She’s an interesting person and I really wanted to help her figure …

MIND Diet Prevents Memory Loss

Researchers at Rush University have developed a diet (the MIND diet) that appears to be associated with significantly reduced cognitive decline in aging. The diet was developed from three sources of information: the Mediterranean diet (as elsewhere on this blog), the DASH diet for the prevention of hypertension, and a review of the literature on the effects of specific dietary components …

Memory and Cognitive Problems

Memory and/or cognitive problems are the rule rather than the exception in people with mood disorders1. There are a number of reasons for this and figuring out the best approach to these problems is tricky. Mood episodes (episodes of mania, hypomania or depression) appear to be harmful to the brain. Studies find that those with the largest number of episodes …

exercise and genes

Exercise affects Genes – Increased BDNF

Today we look at how exercise affects genes (previous article on neurotransmitters and exercise can be read here), in particular we focus on the effects of exercise on the gene that codes for BDNF. Brain-derived neurotrophic factor (BDNF)— or “the fertilizer of the brain” as Dr. Mohammad Alsuwaidan nicknames it— is a protein fundamental for the growth and protection of neurons …

Brain Cell Formation in Older Brains

Cell formation. Readers of this blog may recall that we reported last year the discouraging findings from Dr. Pasco Rakic (professor of neuroanatomy at Yale University) that there is very little neurogenesis (creation of new neurons) in the brains of older primates (including humans). Now, an article by Kristy Spalding published a few months ago in Cell suggests that the …

Brain Derived Neurotrophic Factor (BDNF) May Prevent Alzheimer’s

Higher blood levels of brain-derived neurotrophic factor (BDNF) appear to protect against Alzheimer’s disease (AD) and other types of dementia, that is the result of a study is published in JAMA Neurology this past month by Sudha Seshadri, M.D., a professor of neurology at Boston University and his colleagues. BDNF is “growth hormone” for the brain. It enhances the creation of connections between …

Mediterranean Diet and Depression

Boost your brain power naturally! Try this simple intervention to reduce depression, stroke, heart disease and improve cognition. Does that statement make you a bit wary? A recent meta-analysis of 22 studies spanning two decades finds that the Mediterranean diet is associated with significant reductions in the risk of depression and stroke, and significant improvements in cognition. Across the studies, …

Cognition Enhancing Apps

An experimental computer program is associated with improved attention and working memory in people over age 60, even 6 months after training. Somewhat fuzzy-brained after a poor night of sleep I ran across this summary of a paper that was just published in the prestigious scientific journal Nature (Anguera JA et al., Nature 2013 Sep 5; 501:97). Where could I test drive this application, …

My Brain Isn’t Working

 Difficulties with cognition and focus are almost universal in folks with moods. In the scientific literature there have been attempts to distinguish between mood related problems and problems that tend to persist regardless of mood state. There is probably nothing that can more profoundly affect our brain’s ability to focus than an episode of depression or mania. These functional brain …

Ginseng

If you are a ginseng believer, then ginseng is the one supplement that all of us should be taking. Russian scientist Israel Brekhman coined the term “adoptegens” to refer to agents that helped individuals deal with stress. The prime example of this, in his view, was ginseng. [If you are interested in an example of the controversy that surrounds many …

Memory, Stress and Aging

Many older people are concerned about impaired memory, and the relationship between memory, stress, and aging can be difficult to untangle. Obviously worry about memory problems can be a source of anxiety and stress. But can stress and anxiety be a cause of memory problems? And if so what can be done about it? Elsewhere we will be talking about …

Brain Power

Problems with memory are common for people with depression (and the rest of us, as we age, as well). Although the most important thing to do to improve brain function is to address mood extremes, there are often residual problems, and sometimes there are negative brain effects from the medications that help stabilize mood. A wonderful older man who came …