Does bipolar disorder cause problems with memory, attention focus, speed of thinking and cognition? Does depression cause dementia, or does it just feel like it? Are memory problems and cognition issues caused by the medications that control mood episodes? Is there anything one can do about troubles in thinking and memory related to mood issues? “Suddenly becoming demented” is a …
Depression and Altered Learning
Depression, particularly recurrent depression, has pretty significant effects on how we perceive the world and how well we make plans for the future. In an article published in Biological Psychiatry in March 2020, Tobias Kube and co-authors develop a model of how depression affects critical cognitive processes that expands and extends the traditional model of cognitive changes associated with depression …
Physical Symptoms without Physical Disease – Nancy
A new website designed for people experiencing physical symptoms that are not traceable to physical disease offers clear, scientific information, and also hope for those patients who sometimes spend years in the medical system trying to get relief for pain and other symptoms only to be told that nothing is wrong. The site refers to these symptoms as “functional symptoms.” …
Move It
You have the potential to change your life. There is an almost magical system for activating hundreds of genes associated with better health and better brain function that you have access to. And it won’t cost you. I have written a lot about this amazing system, but this video does a better job than any of my posts. For those …
Intermittent Fasting and Brain Health
Conventional wisdom, especially in the realm of diet and health, often turns out not to be right. Conventional wisdom (as it happens, heavily subsidized by grants from the Kellogg Foundation) has argued that “breakfast is the most important meal” and “fasting diets are unhealthy.” An article published in the New England Journal of Medicine by Casazza in 2013 suggested that the …
TV Watching Leads to Impaired Cognition
How can we build up foundational, long-lasting healthy habits while young? We know it’s important—a perennial question, if not one we face day-to-day. By building those habits early on, we can set ourselves up for healthier living long-term, and place our children on a better track for a healthier, more positive adolescence and early adulthood. In fact, the habits we …
Aerobic Exercise Stimulates Neuron Growth
Moderate aerobic exercise appears to be the best form of exercise to stimulate neuron growth. One of the great challenges facing anyone who has wrestled with depression is how best to counteract the negative effects on brain development and cognitive function that have clearly been linked to recurrent depression. Depression leads directly to reductions in the brain’s growth hormone (brain …
Exercise and Stress – How Exercise Prevents Depression
Exercise seems to reduce stress. But how does this work? And what about exercise effects on depression? An article in the New York Times summarizes a recent publication in the journal Cell which may explain how exercise prevents depression. A wealth of research shows that regular exercise reduces the risk of depression. A very large study in Britain, for example, suggested that …
Exercise affects Genes – Increased BDNF
Today we look at how exercise affects genes (previous article on neurotransmitters and exercise can be read here), in particular we focus on the effects of exercise on the gene that codes for BDNF. Brain-derived neurotrophic factor (BDNF)— or “the fertilizer of the brain” as Dr. Mohammad Alsuwaidan nicknames it— is a protein fundamental for the growth and protection of neurons …
Sleep and the Lunar Cycle
One of our readers wondered if bipolar people are more sensitive to lunar cycles. I could not find any evidence for that, but I did run across a recent research report suggesting that everyone (bipolar or not) may have a sleep cycle that corresponds to the phase of the moon. Researchers at the University of Basel studied 33 people and …
Evolutionary Psychology and Understanding Depression
We are glad to finally have a summary of a fascinating conversation with Dr. Julio Ozores up on this site in our “Conversations” series. Dr. Ozores challenges us to think about depression in a new way. Although many of us struggle with the negative effects of depression in our lives, are (or were) there benefits to depression that have led …
Passing on PTSD to Children
At a recent scientific meeting, Rachael Yehada showed that traits that are related to posttraumatic stress disorder PTSD can be passed on to children during pregnancy. Mothers in New York City who were pregnant on September 11, 2001 and developed post-traumatic stress disorder (PTSD) had children with low cortisol in their blood (a sign of PTSD). But if the fathers …
Brain Cell Formation in Older Brains
Cell formation. Readers of this blog may recall that we reported last year the discouraging findings from Dr. Pasco Rakic (professor of neuroanatomy at Yale University) that there is very little neurogenesis (creation of new neurons) in the brains of older primates (including humans). Now, an article by Kristy Spalding published a few months ago in Cell suggests that the …
Befriending Stress
A colleague recommended this fantastic TED talk by Kelly McGonigal on the cardiovascular and social benefits of befriending stress (and potentially other negative emotions) as opposed to fearing these types of feelings. Kelly offers a fascinating perspective on oxytocin as a stress hormone that serves as a mechanism for resilience, helping people connect with others in times of challenge. Kelly …
Extreme Moods and Memory
I can think of no better example of the phenomenon of state-dependent learning than the mother of two who came into my office one early Fall morning experiencing extremely intense emotions (racing thoughts, and panic attacks) who had had a very similar mood experience 10 years ago when she gave birth to her first child. As the result of the …
Sleep Deep Cleans Your Brain
Beep, beep, beep, beep! Snooze……Beep, beep, beep, beep! You open your eyes, roll out of bed and start wondering why you stayed up so late to watch another episode of your favorite TV series, play another video or computer game, or catch up with your friends, etc. We have busy and full lives, which results in less and more disrupted …
Long Term Antipsychotics – Adverse Effects on Brain?
This post is a bit off topic. I have tried to not focus on medication issues in this blog on the grounds that there are many, many websites that talk about medications and very little else. However one of the blog’s most loyal readers sent in an email about long term antipsychotic medications and potential adverse effects on brain function …
Do Maternal Antidepressants (SRI’s) Cause Autism in Their Children?
Maternal Antidepressants. Two studies have suggested a link between prenatal exposure to antidepressant medication and autism spectrum disorders. We are pleased to learn: that does not appear to be the case! Not surprisingly, the studies mentioned above received a lot of attention and created a lot of concern for women taking antidepressant medications, and their partners, who planned to have …
Changing Hormone Levels and Mood
I was on the phone yesterday having an urgent consultation with a woman we have worked for 15 years. She has had a pretty straight forward history of depression and anxiety that we’ve treated primarily with antidepressants and cognitive behavioral therapy. She’s had a good response to this treatment approach. The two things about her depression that are a little …
Oxytocin and Maternal Depression
There is lots of interest these days in how maternal depression affects kids, and also in how to prevent those effects. Recent research has suggested that the hormone oxytocin may play an important role in what happens. A nice review of this literature appeared in the most recent issue of the American Journal of Psychiatry. The authors note that the …